SkinCeuticals
Discoloration Defense
Discoloration Defense
- redeem Free Samples
- undo 30-Day Free Returns
- local_shipping Free Shipping
Couldn't load pickup availability
Discoloration Defense
Discoloration Defense Product Details
Daily dark spot corrector targets visible skin discoloration for brighter, more even-looking skin.
Discoloration Defense is a layerable, daily-use dark spot corrector clinically proven to reduce the appearance of key types of skin discoloration in all skin tones, including hard-to-treat forms such as stubborn brown patches and post-acne marks. Formulated with 3% tranexamic acid, 1% kojic acid, 5% niacinamide, and 5% HEPES, this serum for dark spots improves the appearance of skin discoloration, brightens skin, and evens skin tone in as early as 2 weeks.
Benefits
- Features a synergistic blend of anti-discoloration ingredients to reduce the appearance of skin discoloration, improve brightness, and minimize the recurrence of discoloration (with continued use)
- 60% average improvement in the appearance of stubborn brown patches*
- 34% average reduction in post-blemish marks in deeper skin tones**
- Paraben-, fragrance-, silicone-, and hydroquinone-free
- Ideal at-home complement to professional skin discoloration treatments, such as chemical peels or non-ablative laser; always consult with a physician for individual skin discoloration serum routine recommendations
- *Protocol: Average results shown. A 12-week, single-center, clinical study was conducted on 50 females, ages 25 to 60, Fitzpatrick I-IV, with mild to moderate facial skin discoloration, including stubborn dark spots, post-acne marks, and uneven skin tone. Discoloration Defense was applied to the face twice a day in conjunction with a sunscreen. Efficacy and tolerability evaluations were conducted at baseline and at weeks 2, 4, 8, and 12. **Protocol: A 12-week, single-center, clinical study was conducted on 51 female subjects, Fitzpatrick V-VI, with visible signs of skin discoloration/hyperpigmentation, including post-inflammatory hyperpigmentation and melasma. Discoloration Defense was applied to the face twice a day in conjunction with a sunscreen. Efficacy and tolerability evaluations were conducted at baseline and at weeks 2, 4, 8, and 12.
Key Ingredients
Paraben-Free
Gluten-Free
Fragrance-Free
Silicone-Free
Hydroquinone-Free
3% Tranexamic Acid
This synthetically-derived ingredient minimizes the recurrence of skin discoloration and stubborn brown patches with continued use.
1% Kojic Acid
Naturally produced by certain fungi, kojic acid helps improve skin brightness.
5% Niacinamide
Also known as vitamin B3, this water-soluble vitamin is found naturally in yeast, meat, fish, milk, eggs, green vegetables, beans, and cereal grains. It has been shown to help reduce the appearance of skin discoloration.
5% Hepes
This synthetically-derived exfoliant activates natural enzymes in the skin to help break the bonds that bind dead skin cells to the surface for even exfoliation.

Nailo Perks
-
local_offer
Up to 50% Off
Sitewide savings on SkinCeuticals bestsellers — limited time only.
-
local_shipping
Free Shipping
Free standard shipping on every order — no minimum.
-
autorenew
30-Day Free Returns
Change your mind? Return any item within 30 days for a full refund.
-
redeem
Free Samples
Every order includes free deluxe samples with your purchase.
Why SkinCeuticals?
Pharmaceutical-grade actives, clinically proven results, and the science of skin health — find out why SkinCeuticals stands apart.
|   | Nailo | Other Brands |
|---|---|---|
| Dermatologist-developed formulas, powered by pharmaceutical-grade antioxidants | ||
| Clinically proven results backed by 15+ years of peer-reviewed research | ||
| The #1 antioxidant brand recommended by dermatologists worldwide |
Testimonials
-
New favorite
I’m using this product for some time now and will continue, it’s very lightweight and it’s feel on my skin absorbs quickly and does not feel greasy with consistent use my skin looks brighter and smooth and even!
Anna
-
The BEST products!!!
I've used this product for some time now and will continue. My complexation feels smooth and refined. I get several compliments, people have told me I don't have any wrinkles. Skincuticals are my every day products, they're expensive but worth it.
Earthquake
-
New favorite serum
This is an amazing serum that has now replaced my former vitamin c. This absorbs so quickly into the skin, and I can wear it under makeup without it pilling. I don’t notice it leave any type of tint either which is a plus. I have extremely sensitive skin and have been able to use this with zero issue.
KellyL